BACKGROUND
As the setting change in which patient care is provided, so do the risks and complexities associated with care.
Patients with central venous catheters (CVCs), particularly those for whom long-term vascular access is needed, are seen increasingly in the inpatient, outpatient, and home care setting.
The process of inserting these catheters disrupts skin integrity and increases the risk of bacterial infection. These infections may result in serious harm to the patient, including death.
It has been estimated that CVCs are associated with almost 90% of all bloodstream infections. Strict adherence to guidelines has demonstrated that these infections are largely preventable.
COST
Central line-associated bloodstream infections (CA-BSI) prolong hospitalization by approximately 7 days and have an estimated attributable cost of between $3,700 and $29,000.
MORTALITY
Approximately 50% of patients in an Intensive Care Unit have a CVC accounting for about 15 million catheter days each year.
It has been estimated that there are approximately 250,000 CA-BSIs each year and studies have suggested that mortality attributable to these infections is between 4% and 20% resulting in an estimated 500 to 4,000 patient deaths each year in the U.S.
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The central line bundle consists of five key components:
Hand Hygiene
Alcohol-based hand rubs have been shown to reduce HAIs and should be used before, during and after central line placement as follows:
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 | | Before and after palpating | | | the catheter insertion site during site assessment
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 | | Before and after inserting, | | | replacing, accessing, repairing, or dressing an intravascular catheter
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 | | Between patients | | | |
 | | Hand Hygiene
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 | | Maximum barrier precautions
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 | | Optimal catheter site selection | | | with the subclavian vein as the preferred site for on-tunnelled catheter
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 | | Daily review of line necessity | | | with prompt removal of unnecessary lines.
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